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- AfCS-Nature Signaling Gateway
Joint resource from Alliance for Cellular Signaling, featuring meetings, workshops, primary research papers, reviews, database of molecules and protein data, updated in Durham, NC and editorial office at Nature Publishing Group, London, UK. Full access requires registration.
- Cell Intelligence
Experimental research over two decades into the question of whether cells have a central signal integration system, including author profile, at Northwestern University, Evanston, IL.
- Cell Signaling Networks Database
Resource devoted to information on pathways from NIHS, Japan.
- Cell Signaling Pathways
Educational resource to browse or download powerpoint slides, on apoptosis, cell cycle, cytokines, growth factors, gene regulation, ion channels, neurotransmission, and the role of nitric oxide. Links to technical support and customer services of Sigma-Aldrich Co.
- Cell Signaling Technology, Inc.
Phospho-specific Antibodies and other Innovative Discovery Tools for Cell Signaling Research.
- Cell Signalling
Research focused on phosphoinositide 3-kinases, in lipid phosporylation within cell membranes. Phospholipids initiate cascades for cellular activities. Related links to groups at the Ludwig Institute for Cancer Research, London, UK.
- Cyclic GMP
Overview of the receptor interaction and intracellular pathway, focusing on the role of nitric oxide, and their clinical relevance. Includes diagrams, animations and links to related pages and free access publications.
- Drastic (Database Resource for Analysis of Signal Transduction In Cells)
A database of plant genes regulated in response to infection or other stresses.
- Dynamic Signaling Maps
Web-based software for creating, editing, annotating, and storing biological signaling pathways, doing consistency checks when integrating data from multiple sources, producing biomolecular network maps, and integrating pathways with protein-protein interaction data.
- G-Protein-Coupled Receptors Mutant Database
Database devoted to mutants in G-protein-coupled receptors.
- Handbook of Receptor Classification and Signal Transduction
Antibodies, enzymes, lipids, cytokines, growth factors, G proteins and protein phosphorylation, in areas of apoptosis gene regulation, ion channels, neurotransmission and cytoskeleton. PDF downloads or from Sigma-Aldrich Co.
- Insulin Signalling Pathway
Flash presentaion of mechanisms and protein structure of hormone and receptor, linked to regulation molecules, proteins involved and their molecular interactions. Students' project at Univerisity College of London, UK.
- Ion Channels and Thyroid Hormones
Research in the modulation of synaptic function by hormones and their non-genomic action in the amphibian neuromuscular junction, at the Department of Physiology, UCC, Bayamón, PR.
- KEGG
KEGG Regulatory Pathways -- a collection of graphical pathway maps, ortholog group tables, and molecular catalogs. Contains a few signaling pathway maps related to medical conditions.
- Levin and Buck Lab
Research on bicarbonate regulation of second messenger cAMP pathway, publications, related links and staff contacts at Department of Pharmacology, Weill Medical College of Cornell University, New York City.
- Mammalian MAPK Signalling Pathways
Signaling related to the mitogen-activated protein kinase pathway, with links to SAPK and p38, and related sequennces, from Ontario Cancer Institute, Toronto, Canada.
- Protein Kinase Resource
Compendium of information on the protein kinase family of enzymes.
- Publicover Research Group,
Signaling studies in human bone cell and sperm, before fertilization at University of Birmingham, UK.
- Receptors, Signaling and Proteomics
Research on growth factor transforming and GPI-linked receptors, with links to relevant references. Includes profiles of group members at NRC Biotechnology Research Institute, Canada.
- SenseLab
International network of researchers developing comprehensive multidisciplinary models of neurons and neural systems, using the olfactory receptors pathway as a model, arranged as six databases, maintained at Yale University.
- Signal Transduction in the Nervous System
Signal Transduction Laboratory at East Carolina University Brody School of Medicine. Research focuses on signaling pathways activated in the nervous system during development, disease and aging.
- Signal Transduction Knowledge Environment
Resources in the field offered by Science Online. Requires registration, and subscription fee for most content.
- SPAD: Signaling Pathway Database
Diagrams of pathways, linking to sequences of growth factors, cytokines and hormones, and to their genetic information. Part of project at the Graduate School of Genetic Resources Technology, Kyushu University, Japan.
- The Holmgren Lab
Research focused on the Hedgehog (Hh) signaling pathway, in development of invertebrate and vertebrate appendages, and differentiation in the fruit fly. Includes glossary with information on other pathways, publications linked to NML, staff photos and contacts at Northwestern University, Evanston, IL.
- The Nuclear Receptor Resource
A collection of databases devoted to nuclear receptors, such as steroid receptors.
- The WWW Virtual Library: Cell Biology: Signal Transduction
Annotated index of major online resources dealing with signal transduction in cell growth, differentiation and stimulus response.
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