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Software

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    • EMBOSS
      The European Molecular Biology Open Software Suite. An open source project started by the EMBnet community in order to replace proprieatry systems like GCG.
    • AcaClone pDRAW32
      Freeware DNA cloning, analysis and visualization software.
    • AG BIODV Software
      Links to software developed by the AG BIODV group. Tools for consensus, alignment and definition. Both downloads and executables.
    • AnnHyb - Nucleotidic Sequence Manager
      Free software for working with and managing nucleotide sequences in multiple formats. Many features including sequence annotation, restriction analysis, pattern searching, retrieval from servers. Released under GNU Public Licence.
    • Array Genetics
      Bioinformatics programs, including MendelBase.
    • Artemis: A DNA Sequence Viewer and Annotation Tool
      Java program to display a DNA sequence, annotated with features, ORFs. Reads many input formats.
    • BSML - Bioinformation Sequence Markup Language
      Extensible language specification and container for bioinformatic data.
    • Computer Program for Polyphasic Taxonomy Analysis
      The proBiosys suite of programs compares phenetic, chemotaxonomic and nucleic acid sequence data. Algorithms for polyphasic taxonomy are available to construct Dendrograms, the suite is simple to use.
    • DARWIN
      An interactive tool for peptide and nucleotide sequence analysis
    • DNA-Star - Lasergene
      Commercial sequence analysis and manipulation suite for Windows and Macintosh.
    • GDE for Linux
      An integrated linux environment for bioinformatics and evolutionary analysis based on the Genetic Data Environment (GDE). Contains binaries for Linux and Mac OS X, documentation, screenshots, references, and organism specific interfaces.
    • Genalysis Genome Analysis Toolkit
      Commercial tool for comparing whole genomes or large genetic sequences. Outputs lists of matches and dot-plots and supports web-based BLAST searches.
    • GeneRunner for Windows
      A fairly old sequence analysis tool for everyday lab use. Formerly a commercial product - now "abandonware."
    • GeneticXchange
      Software for life science discovery; enterprise-level data integration and desktop biologists.
    • Gints
      Object-oriented regulation network simulator written in Java. Includes downloadable software and documentation. The site is in French and English.
    • HMMER - profile hidden Markov models for sequence analysis
      Sean Eddy's tools to build HMMs from multiple alignments, align sequences to HMMs, calculate e-scores, and other tools
    • Linux Software Encyclopedia - Bioinformatics
      Links to Bioinformatics software for Linux. From the Linux Software Encyclopedia.
    • LucID Professional
      Software for creating interactive keys for biology, taxonomy, medicine, and agriculture.
    • Meta-MEME v2.0.1
      Software toolkit for building and using motif-based hidden Markov models of DNA and proteins - from the Univ. of California-San Diego.
    • Metalifesocieties
      Makes available various bioinformatics algorithms, which perform all essential tasks in sequence analysis and sequence-based predictions.
    • Molecular Evolutionary Genetics Analysis (MEGA2) software
      Provides free downloadable MEGA2 software for use in comparative sequence analysis of genetic data. Program for Win32 platforms.
    • NCBI BLAST
      BLAST (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA.
    • Paracel BLAST
      Software for accelerated parallel BLAST searching
    • PHRED - Base-Calling Software with Quality Information
      A widely-used program for calling DNA sequence bases from sequencer trace files.
    • Phred/Phrap/Consed System Home Page
      basecaller / assembler / sequencer finisher and related tools from the UW Genome Center.
    • Premier Biosoft International
      Developers of software for real time PCR primer design, TaqMan, molecular beacons, DNA microarray analysis, drawing restriction plasmid maps, gateway cloning experiments, protein interaction network and functional genomics.
    • PubCrawler - An Update Alerting Service for PubMed and GenBank
      Software and an online service for periodically performing predefined searches at NCBI, reporting new results by email or on the web.
    • Public Domain Software in Biology
      The aim of this project is to build the database of public domain software in biology and to distribute these software on-line as well as off-line. These computer software developed by people for people and are available free to potential users. The software collected on this site will be available on-line free for users via internet (e.g. FTP, Email Server, web browser ).
    • Sequence Analysis for Mac OS X
      A freeware Mac OS X application written in Java that does many standard types of DNA and protein sequence analysis tasks.
    • Sight: Extendable parallel system for automatic genome analysis
      Software for analysing all potential genes in a defined genome region. Given two marker names, can output reports of genomic features between them. Features for converting between naming systems, sequence retrieval, E-PCR, gene prediction, similarity search, protein pattern search, and report formatting. Written in Java.
    • Slcview
      Open source program which allows automated generation of high quality clustergrams and tree images from .cdt files.
    • Software for Statistical Folding and Rational Design of Nucleic Acids
      Sfold predicts probable RNA secondary structures, assesses target accessibility, and provides tools for the rational design of RNA-targeting nucleic acids. The web server version is free for academic use.
    • STRING
      Search for Tandem Repeats IN Genomes -- Includes C source code and examples.
    • T-Coffee
      T-Coffee is a multiple sequence alignment package using a novel algorithm, available for Unix, MS-DOS, and Mac OS X. Includes binaries, source, references, and documentation.
    • The ARB Project
      A free sequence database application for Unix. It includes a sequence editor, several sequence aligners, phylogeny reconstruction tools, probe/primer search and generation, genome annotation and visualization. In addition to the integrated user-interface the ARB database can be accessed using Perl or C.
    • The FASTA package of sequence comparison programs
      William Pearson's package for fast sequence comparison
    • The Sanger Centre: Software
      Production software used at the Sanger Centre, physical mapping software, informatics and analysis software, and data formats
    • VectorNTI
      Commercial software suite for analysis and manipulation of DNA and protein sequences
    • Verbumculus Genetic Sequence Analyzer
      An interesting tool to discover and visualize over- or under-represented words in genetic sequences. Executable for Sparc-Solaris, Sparc-Intel or Linux-Intel. Also available as a Java applet.
    • WU-BLAST Archives
      WU-BLAST: The Washington University BLAST. "...faster at any sensitivity, more sensitive at any speed, the first BLAST with gapped alignments and statistics."
    • XDigitize
      A visualization software system for evaluation of hybridisation experiments.
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